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Chang-Han Lee
- Dec 29, 2023
- 2 min
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations
https://www.science.org/doi/10.1126/scitranslmed.adg6822 Editor’s summary The autoimmune disease immunodysregulation polyendocrinopathy...
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Chang-Han Lee
- Dec 29, 2023
- 1 min
HIV vaccines induce CD8+ T cells with low antigen receptor sensitivity
https://www.science.org/doi/full/10.1126/science.adg0514 Editor’s summary Although preclinical work in SIV- and SHIV-challenged nonhuman...
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Chang-Han Lee
- Dec 29, 2023
- 1 min
Divergent molecular networks program functionally distinct CD8+ skin-resident memory T cells
https://www.science.org/doi/10.1126/science.adi8885 Editor’s summary Tissue-resident memory T (TRM) cells are long-lasting memory T cells...
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Chang-Han Lee
- Dec 29, 2023
- 1 min
PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma
The combination of atezolizumab plus bevacizumab (atezo/bev) has dramatically changed the treatment landscape of advanced HCC (aHCC),...
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Chang-Han Lee
- Dec 29, 2023
- 1 min
아스트라제네카, 12억 달러에 중국 그레이스엘바이오 인수
- CAR-T 세포치료제 분야 파이프라인 강화 http://www.medisobizanews.com/news/articleView.html?idxno=112870 자가 CAR-T는 신체 면역반응의 핵심 부분 인 환자의 면역 T세포를 질병을...
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Chang-Han Lee
- Dec 22, 2023
- 2 min
Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma
https://link.springer.com/article/10.1186/s12943-023-01886-9 Background Commercial anti-CD19 chimeric antigen receptor T-cell therapies...
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