Articles_Antibody

Dec 29, 20231 min

PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma

The combination of atezolizumab plus bevacizumab (atezo/bev) has dramatically changed the treatment landscape of advanced HCC (aHCC),...

Chang-Han Lee

Dec 22, 20233 min

Articles_Antibody

65th ASH Annual Meeting-Efficacy and Safety of Less Frequent/Lower Intensity Dosing of Talquetamab in Patients with Relapsed/Refractory Multiple Myeloma: Results from the Phase 1/2 MonumenTAL-1 Study

https://www.sciencedirect.com/science/article/pii/S0006497123076139 Introduction: Talquetamab (tal) is an off-the-shelf, T-cell...

Chang-Han Lee

Nov 28, 20232 min

Articles_Antibody

Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau

Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils PNAS October 6, 2023 120 (41)...

Chang-Han Lee

Nov 28, 20232 min

Articles_Antibody

A CD3 humanized mouse model unmasked unique features of T-cell responses to bispecific antibody

Blood Advances OCTOBER 23, 2023 https://pubmed.ncbi.nlm.nih.gov/37871327/ Key Points · BsAb treatment causes temporary T cell...